Seronegative rheumatoid arthritis, rheumatoid factor cross reactive idiotype expression, and hidden rheumatoid factors.

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Seronegative rheumatoid arthritis, rheumatoid factor cross reactive idiotype expression, and hidden rheumatoid factors.

The major rheumatoid factor cross reactive idiotype (RCRI), defined by prototypic monoclonal rheumatoid factors (RFs), is expressed as a dominant idiotype by pokeweed mitogen induced plasma cells obtained from seropositive (RF+) patients with rheumatoid arthritis (RA). Some patients who meet clinical diagnostic criteria for RA set by the American Rheumatism Association fail to express RFs at an...

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Differential Expression of Rheumatoid Factor-Associated Cross-Reactive Idiotypes in Iranian Seropositive and Seronegative Patients with Rheumatoid Arthritis

High levels of rheumatoid factors (RF) are detectable in serum of the majority of patients with rheumatoid arthritis (RA), but 5-10% of patients remain seronegative (SN). Despite clinical and genetic similarities between these two subsets of RA, it has been proposed that they may be regarded as distinct clinical entities. Methods: In the present study a panel of monoclonal antibodies (mAb) rec...

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differential expression of rheumatoid factor-associated cross-reactive idiotypes in iranian seropositive and seronegative patients with rheumatoid arthritis

high levels of rheumatoid factors (rf) are detectable in serum of the majority of patients with rheumatoid arthritis (ra), but 5-10% of patients remain seronegative (sn). despite clinical and genetic similarities between these two subsets of ra, it has been proposed that they may be regarded as distinct clinical entities. methods: in the present study a panel of monoclonal antibodies (mab) reco...

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Differential expression of rheumatoid factor-associated cross-reactive idiotypes in Iranian seropositive and seronegative patients with rheumatoid arthritis.

INTRODUCTION High levels of rheumatoid factors (RF) are detectable in serum of the majority of patients with rheumatoid arthritis (RA), but 5-10% of patients remain seronegative (SN). Despite clinical and genetic similarities between these two subsets of RA, it has been proposed that they may be regarded as distinct clinical entities. METHODS In the present study a panel of monoclonal antibod...

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second patient with seronegative rheumatoid arthritis and treatment with diet

second patient with seronegative rheumatoid arthritis and treatment with diet

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ژورنال

عنوان ژورنال: Annals of the Rheumatic Diseases

سال: 1989

ISSN: 0003-4967

DOI: 10.1136/ard.48.6.488